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Laboratory research and development

Thermo Scientific TraceGOLD GC
Column with SafeGuard extends analytical
lifetime and maintains chromatographic performance

The Thermo Scientific TraceGOLD GC Column with SafeGuard, combines an analytical gas chromatography (GC) column with a built-in guard column. The SafeGuard feature extends the life of the analytical column without compromising its chromatographic performance. Available in a range of guard column lengths and analytical column specifications, TraceGOLD™ GC Columns with SafeGuard are suitable for use in a broad spectrum of applications that necessitate the injection of involatile sample matrix, particularly in environmental, forensic, food safety and petrochemical analyses. 

To prolong their life, GC columns are routinely cut to remove contaminant deposits. With conventional columns, however, this practice reduces the separation accuracy, peak resolution and column quality over time. With the TraceGOLD GC Column with SafeGuard, on the other hand, users can cut columns during routine maintenance with no impact on the chromatography performance of the analytical column.

For further information, view website: www.thermoscientific.com/tracegold 
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Chromatography videos bring technology to the
desktop with the Chromatograph Resource Center

Thermo Fisher Scientific's wide range of technical chromatography videos, are available to watch on the Thermo Scientific Chromatography Resource Center (CRC). Giving instant access to the chromatography experience and expertise of Thermo Fisher Scientific, these videos contain updates and technical explanations of topical issues in HPLC, GC and SPE. The full portfolio of presentations, hosted on the Chromatography videos channel, is accessible to view via the CRC homepage.

With 6000 technical application notes detailing chromatographic and protocol specifications, as well as a comprehensive library of background literature, the CRC provides a complete resource for the analytical scientist. In addition,
the HPLC method transfer calculator and GC column selector tool are provided to smooth the transition into new chromatography applications.

To see what is new from Thermo Fisher Scientific view website: www.thermoscientific.com/crc or http://www.youtube.com/chromatographyvideos 
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Dolomite Mitos P-Pump Basic: Providing a simple,
reliable and cost effective solution for pulseless liquid flow

Following the global success of the Mitos P-Pump, microfluidics expert Dolomite has added the Mitos P-Pump Basic to its range, offering a flexible and cost effective solution for microfluidic systems operating from nl/min to ml/min.

Using the innovative pulseless Mitos P-Pump technology, the Mitos P-Pump Basic features data logging and control via free PC software. With excellent response time and accuracy, it is ideal for use with viscous liquids and microfluidic systems where highly stable flow is required for applications such as cell manipulation, microreactions and droplet formation.

Operating over a wide pressure range of 0 - 10bar, the Mitos P-Pump Basic offers smooth fluid flow increasing quality and stability of microfluidic experiments, such as droplet generation, compared to traditional syringe pump technology. features a lockable pressure chamber which is easily accessible and accommodates a wide range of standard and non-standard fluid vessels. With the ability to contain samples from 100μl to 30ml, the Mitos P-Pump Basic uses fluid directly from the container eliminating sample waste.

The Mitos P-Pump Basic can be used together with Dolomite's Mitos Flow Rate Sensor and Sensor Display Basic allowing users to measure micro-scale flow rates. Unique experimental profiles can be easily set up using LabVIEWTM.

For further information on Dolomite's range of pumps as well as a complete portfolio of microfluidic products including chips, connectors/ interconnects, valves and custom devices, view website:
www.dolomite-microfluidics.com   Refer to page 249

Microfluidic expert launches versatile
pump solution offering increased user flexibility

Dolomite, a world leader in microfluidic design and manufacture, has introduced the Mitos P-Pump Remote offering a versatile solution for microfluidics, allowing users a seamless way to control their experimental environment.

Operating over a wide pressure range of up to 10bar, the Mitos P-Pump Remote is the latest addition to Dolomite's Mitos P-Pump range featuring an innovative pneumatic fitting which allows users to simply attach Dolomite Remote Chambers or custom chambers with a push-click action reducing downtime between experiments.

Multiple remote chambers can be used which are easily accessible for cleaning or sterilisation broadening experimental possibilities and increasing efficiency within microfluidic systems. For applications requiring temperature control or agitation of  particles, such as cell manipulation, the remote chambers can be placed on a hotplate, magnetic stirrer or incubator.

The Mitos P-Pump Remote can be used together with Dolomite's
Mitos P-Pump Remote Chamber 30, a glass pressure chamber which connects securely to the pump via a pneumatic fitting located on the base and can contain fluid samples from 100μl to 30ml. The Mitos P-Pump Remote is also available as Mitos P-Pump Remote Basic featuring data logging and control via free PC software.

For further information on Dolomite's range of pumps as well as a complete portfolio of microfluidic products including chips, connectors/ interconnects, valves and custom devices, view website:
www.dolomite-microfluidics.com   Refer to page 249

TTP LabTech's Mirrorball offers equivalent
data with minimal changes to assay protocols

TTP LabTech's data results of a valuable benchmarking study using its Mirrorball® antibody discovery system, accurately demonstrates that Mirroball offers equivalent data to the discontinued ABI 8200 FMAT® instrument, with minimal changes to assay protocols.

Mix-and-read assays, first popularized as FMAT assays, were developed to overcome the problems associated with automating ELISAs particularly in cell-based methods. This new comparative study has used the FMAT assay to look at bead-based quantitation of a soluble protein (rabbit IgG) and antibody binding to EGF receptors expressed in A459 cells. The Mirrorball system scanned the entire well, and FMAT reported data from only a 1 mm2 area in each well. Beads were identified by laser scatter on Mirrorball and fluorescence on FMAT. The Mirrorball system could enumerate beads in all wells, in contrast to FMAT which could not detect all beads below 1 ng/mL rabbit IgG.

TTP LabTech Ltd in profile
Based near Cambridge, UK, TTP LabTech supplies laboratory instrumentation for the healthcare, biotech and pharmaceutical sectors. TTP LabTech's products are designed to increase efficiency, effectiveness, flexibility or overall capability in key biopharmaceutical research processes including compound storage (comPOUND®), low volume liquid handling (mosquito®), fluorescence detection (Acumen®) and antibody discovery (Mirrorball®).

The study demonstrated that the performance of both systems was broadly similar.

For the full application note detailing this comparative study, view website:  http://www.ttplabtech.com/emailers/mirrorball-benchmarking-study.html

For further information about Mirrorball, view website: www.ttplabtech.com/products/mirrorball/overview.html 
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