Thermo Fisher Scientific's advanced
plate options for immunoassay protocols

Thermo Fisher Scientific's large portfolio of immunoassay surfaces ensures you get the best results from your assays. Passive binding surfaces are available to adsorb medium to large biomolecules in a range of orientations. For more specific binding, the Thermo Scientific Nunc CovaLink plates facilitate coupling of molecules bearing a free carboxyl or phosphate group, enabling peptides, haptens and DNA to be effectively coupled. In addition, the Nunc™ Immobilizer amino plate forms stable covalent bonds with the free amino acids or sulfhydryl groups of the biomolecule, eliminating the need for a blocking step. Affinity capture surfaces offer even more specific binding, with reduced variability in molecular orientation and improved signal to noise ratio.

In order to help you to select the best plate format to meet the demands of your application, the interactive and searchable Thermo Scientific immunoassay plate selector guide is a free resource, providing in-depth detail about the range of plates available and their applications.

For furtherinformation and to download the guide, view website: www.thermoscientific.com/oemdiagnostics 

HPLC Method Development Calculator Tools available
on the Thermo Scientific Chromatography Resource Center

Thermo Fisher Scientific provides invaluable assistance with the HPLC Method Development Calculator to chromatographers looking to optimize methods with the latest column technologies. This interactive range of online tools is hosted on the Thermo Scientific Chromatography Resource Center  and helps calculate initial conditions for gradient and isocratic methods.  In addition, an LC column selection tool is provided to assist in the choice of the appropriate column for any application. 

With the ability to significantly reduce the time spent in experimentally defining optimal analysis condition, the HPLC Method Development Calculator provides users with quick and easy access to the technical expertise of chromatographers at Thermo Fisher Scientific.

To access the HPLC Method Development Calculator and to find out how you can benefit from the chromatography expertise at Thermo Fisher Scientific view website:www.thermoscientific.com/crc

Thermo Scientific Revco UxF Series increases
internal space within a small laboratory footprint

Thermo Fisher Scientific's portfolio of Thermo Scientific Revco UxF Series ultra-low temperature (ULT) freezers is available in five sizes, with capacities from 421 to 949 liters (14.9 - 33.5 cubic feet), internal space is maximized, within a small laboratory footprint. In addition, the new design of the cabinet and its vacuum panel insulation allow up to 70,000 2 mL tubes or 118,300 1 mL Thermo Scientific Cryobank tubes to be stored at any one time. Providing advanced temperature uniformity throughout the internal chamber, usable space is maximized, making it the ideal choice for any space restricted laboratories.

Providing outstanding sample protection during long- and short-term cold storage, the Thermo Scientific Revco UxF Series of ULT freezers are available in a number of different size and capacity formats, to suit any storage and space requirements. As a result, users can store large sample numbers, saving valuable time in making stock solutions for subsequent use.

For further information view website: www.thermoscientific.com/revcouxf

Technical library of LC-MS solutions for quick
and easy analysis of PPCPs and pesticides in water

Thermo Fisher Scientific new technical library of LC-MS solutions for water analysis, includes application information on the detection of pharmaceuticals and personal care products (PPCPs) and pesticides.

The technical library, available at: www.thermoscientific.com/lcmswater is a comprehensive and regularly updated searchable resource containing application notes, webinars, technical posters, articles, case studies, videos and web resources for numerous applications, including the analysis of pesticides, PPCPs, herbicides, endocrine disruptors and perfluorinated compounds.

"We designed the LC-MS technical library to give our customers ready access to water and beverage analysis resources that can help them improve and simplify their laboratory operations," said Dipankar Ghosh, Ph.D., strategic marketing manager for environmental and food safety solutions at Thermo Fisher Scientific. "Our innovative LC-MS systems support a wide variety of applications for water and beverage sampling, from targeted and non-targeted screening to quantitative and qualitative analyses. We are committed to making our customers' analyses as easy as possible with solutions that address both existing and future environmental concerns."

The Thermo Scientific EQuan MAX LC-MS solution is ideal for quick and easy detection of pesticides and PPCPs in surface and drinking water, reducing the time required for sample preparation while delivering the sensitivity and selectivity needed to identify analytes of interest. The EQuan MAX system is an automated, high-throughput LC-MS solution that offers improved productivity and simplified assay development. With its unique online sample enrichment technique, scientists can significantly reduce analysis time - from days to minutes. And its high injection volume (1-20mL) enables higher detection limits than conventional LC-MS/MS analysis.

The online technical library, designed as a knowledge transfer tool, provides customers with access to Thermo Fisher's vast application expertise and a variety of technical applications for water analysis. The digital resource is available free at: http://www.thermoscientific.com/lcmswater.

For the latest information about Thermo Fisher solutions and its wide range of applications for water and beverage analysis, e-mail: analyze@thermofisher.com or view website: www.thermoscientific.com/ms  Refer to page 284

NanoSight recognised by Deloitte as
the UK's fastest growing biotech company
in their 2011 Technology Fast 50 rankings

NanoSight, leading manufacturers of unique nanoparticle characterization technology, are in the Deloitte 2011 Fast 50 list of the fastest growing technology companies in the UK. In the world of biotech, NanoSight has made it to number one nationwide and overall is the fastest growing of all technology companies in the South West and Wales region of the UK.

NanoSight has been ranked in the Deloitte 2011 UK Technology Fast 50, which recognises the 50 fastest-growing technology companies in the UK. The company has also been named as a winner in the Technology Fast 500 EMEA 2011 rankings, which recognises the 500 fastest-growing technology companies across Europe, the Middle East and Africa. Both programmes are based on percentage revenue growth over the last five years.
Pictured (top): NanoSight CEO, Jeremy  Warren. (Below): NanoSight founder & CTO, Bob Carr.

NanoSight has grown by more than 800 per cent over the past five years and entered the league table for the first time at 38th in the list. The company is the only South West firm in the annual ranking and the highest-ranking biotech firm nationally.

NanoSight was founded in 2004 by Dr Bob Carr and John Knowles after Carr discovered a technology which allows particles so small they could not be detected by the best optical microscopes to be seen, sized and counted, in just minutes, for a fraction of the cost of electron microscopes. The business was initially supported by funding from Winchester-based venture capitalists Shackleton Ventures and the Bristol office of Yorkshire Fund Manager Equity Partners, supplemented by angel finance accessed through the South West Angel and Investors Network (SWAIN) and London-based Lesmoir-Gordon, Boyle & Co.

Since 2005, NanoSight has grown sales by around 70 per cent annually, year on year, and now employs 23 people in the UK. The firm sells its products all over the world, with around 90 per cent of its sales outside the UK. The most significant growth is in pharmaceuticals and life sciences, where budgets have remained largely unaffected by the global financial condition. There are now more than 400 NanoSight instruments in use worldwide and this number continues to grow as the firm's products are cited almost daily in fresh academic papers.

Jeremy Warren, CEO of NanoSight, commented: "What we sell is unique, and we estimate we are currently only in single digits in terms of percentage of market penetration. So what limits our growth most isn't the market, but having the technical and sales staff to go and sell! The South West has been the ideal place for us to base our business as our universities offer the high-calibre science graduates we're looking for to help us continue to develop the business."

To find out about the company and to learn more about particle characterization using NanoSight's unique nanoparticle tracking analysis solutions, view website: www.nanosight.com and register to receive the next issue of NanoTrail, the company's electronic newsletter.  Refer to page 313