The Journal of Industry and Technology

Industrial Analytical Instrumentation

Euro Technology

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Materials and biophysical characterization technology

Malvern's new OMNISEC GPC/SEC platform
brings ground-breaking performance to the analysis
of polymers, proteins and other macromolecules

A completely new gel permeation/size exclusion chromatography (GPC/SEC) platform from Malvern Instruments breaks new ground in delivering the high performance, ease of use and productivity demanded in today's analytical laboratories. Malvern's innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules.

GPC/SEC is a two-step analytical process that involves separating a sample on the basis of its size and then analyzing the resulting fractions. The technique delivers molecular weight, molecular size and structural information, all of which define the performance of many industrially important materials. Coupling the efficient sample separation of OMNISEC RESOLVE with the fully optimized, multi-detector, information-rich analysis delivered by OMNISEC REVEAL, Malvern has produced a market-leading solution for researchers and formulators developing novel natural and synthetic polymers, pharmaceutical and biopharmaceutical products and foods.

OMNISEC REVEAL includes the following four detectors: refractive index (RI), UV/Vis Photodiode array (UV-PDA), low angle/right angle light scattering (RALS/LALS) and viscometer. Its light scattering detector is the most sensitive on the market meaning it can accurately measure molecular weights as low as 200 Da or injection masses of 100 ng. A new self-balancing viscometer design with a user exchangeable capillary bridge boosts instrument productivity and cuts lifetime costs by extending viscometer life, reducing instrument downtime and minimizing maintenance requirements. Excellent temperature control across the complete module, including the integrated detectors and inter-detector tubing, further boosts the accuracy of all measurements.

OMNISEC RESOLVE consists of a sample degasser, pump, autosampler and column oven, each optimized for precise, high resolution separations. This translates into smooth stable baselines for detector analysis, which in turn boost the accuracy of all measurements. Key features here include a low volume, high efficiency degasser design that enables rapid switchover from one sample type to another, thereby delivering substantial timesaving in busy multi-user labs. The new temperature controlled autosampler eliminates injection waste, minimizing the sample required for routine measurement, and in combination with the column oven maintains all samples under closely controlled conditions throughout the analysis. This is especially important when dealing with materials such as proteins which can be temperature sensitive.

As well as the complete OMNISEC system, OMNISEC REVEAL can be purchased as an individual detector module to add to an existing GPC/SEC system. However, there are substantial advantages to an integrated system, with benefits including: smaller inter-detector volumes, reduced band broadening and better temperature control. These deliver improved sample stability and enhanced accuracy, and the day-to-day productivity efficiencies that stem from using a system that has been fully and optimally integrated to meet modern GPC/SEC requirements.

To find out more about OMNISEC, view website: www.malvern.com/omniseclaunch

Malvern Instruments in profile
Malvern provides the materials and biophysical characterization technology and expertise that enables scientists and engineers to understand and control the properties of dispersed systems. These systems range from proteins and polymers in solution, particle and nanoparticle suspensions and emulsions, through to sprays and aerosols, industrial bulk powders and high concentration slurries. Used at all stages of research, development and manufacturing, Malvern's materials characterization instruments provide critical information that helps accelerate research and product development, enhance and maintain product quality and optimize process efficiency.

Malvern's products reflect their drive to exploit the latest technological innovations and our commitment to maximizing the potential of established techniques. They are used by both industry and academia, in sectors ranging from pharmaceuticals and biopharmaceuticals to bulk chemicals, cement, plastics and polymers, energy and the environment.

Malvern systems are used to measure particle size, particle shape, zeta potential, protein charge, molecular weight, mass, size and conformation, rheological properties and for chemical identification, advancing the understanding of dispersed systems across many different industries and applications.

Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Japan and Korea, a joint venture in India, a global distributor network and applications laboratories around the world.

Malvern and Malvern Instruments are registered trademarks of Malvern Instruments Ltd.

For further information, view website: www.malvern.com

Also view: www.materials-talks.com Twitter: www.twitter.com/@malvern_news and Google +: https://plus.google.com/+malvern 
Refer to page 340

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